Current Issue : October - December Volume : 2016 Issue Number : 4 Articles : 6 Articles
Tulsi leaves have been found to exhibit a wide variety of activities which are very helpful to mankind. In present study, the volatile oil of different species of tulsi (Ocimuma fricanum, Ocimum basillicum, Ocimum gratissimum and Ocimum citriodorum) was taken by hydraulic distillation of the leaves. The diluted volatile distillate was subjected to tests for larvicidal activity. Larvicidal activity test were performed for volatile oil obtained from four different species of tulsi to evaluate the percentage mortality produced by volatile oil of each species of tulsi in the fourth instar larvae of mosquitoes after 24 hrs of exposure. Ocimuma fricanum species was found most efficacious with outcomes of maximum larvicidal activity among all tested groups....
In vitro study of ethanolic, cold and hot-water extracts of Cymbopogon\ncitratus, Moringa oleifera, Ocimum gratissimum and Clerodendrum volubile was determined\nagainst toxigenic Aspergillus flavus. The antifungal efficacies of the medicinal\nplants were investigated using agar well diffusion technique and minimum inhibitory\nconcentration. The phytochemical constituents of the plants were also investigated. It\nwas observed that, hot-water extract of C. citratus was most effective against toxigenic\nA. flavus, cold water extract of M. oleifera was effective against toxigenic A. flavus, the\nmost antifungal effect of O. gratissimum and C. volubile were efficient using ethanolic\nextraction method. One thousand milligrams per millilitres concentration of these\nplant extracts had inhibitory effect on toxigenic A. flavus. The results of phytochemical\nscreening of the plant extracts for the detection of volatile oil, glycoside, tannins and\nsaponins shows that saponin and tannin, were detected in the ethanolic, cold and hotwater\nextract of M. oleifera, O. gratissimum and C. volubile. These result of the research\nindicates that ethanolic extracts of M. oleifera, O. gratissimum and C. volubile are used\nto cure infections caused by toxigenic A. flavus and the extracts may have role as pharmaceutical\nand preservatives....
Background: Acacia hydaspica R. Parker, family leguminosae, is a medicinally important plant. Different plant\nparts are used in various ailments in folk medicine. The current study aimed at investigating the in vitro\nantioxidant, anti-hemolytic and anticancer activity of A. hydaspica.\nMethods: Antioxidant potential was assessed using DPPH, ABTS and â�¢OH, scavenging of H2O2, inhibition of\nlipid peroxidation and �²-carotene bleaching inhibition assays. Anti-hemolytic activity was assessed using H2O2\ninduced hemolysis of RBCs. Anticancer potential was assessed using MTT assay. Spectrometric methods and\nHPLC-DAD analysis was performed for phytochemical screening.\nResults: EC50 values based on reduction of DPPH, ABTS and â�¢OH, scavenging of H2O2, inhibition of lipid\nperoxidation and �²-carotene bleaching for AHB, AHE and AHM were generally lower manifesting potential\nantiradical capacities. The fractions also exhibited significant (P <0.001) anti-hemolytic potential. Regarding\nIC50 values for anticancer activity against HCC-38 and MDA-MB-361 cancer cell lines; AHB, AHE and AHM\nexhibited significant (P <0.001) cyto-selection indices. Plant extracts showed no cytotoxicity against normal\nVero cells (IC50 > 250 �¼g/ml). While significant (P <0.001) cytotoxicity was elicited by these extract/fractions\nagainst cancer cell lines. AHE was the most effective and IC50 was found to be 29.9 �± 0.909 �¼g/ml (SI = 9.83)\nand 39.5 �± 0.872 �¼g/ml (SI = 7.44) against MDA-MB-361 and HCC-38 cancer cells respectively. Higher amounts\nof TPC and TFC were exhibited by AHE and AHB as compared to other fractions. Gallic acid, catechin and\nmyricetin were identified in AHE whereas gallic acid and catechin were identified in AHB by HPLC.\nConclusion: The presence of bioactive constituents in AHE and AHB might be responsible for antioxidant,\nanti-hemolytic and anticancer activities....
Among all the diseases prevailing in the world, cancer has become a big threat to humans. The mortality rate has been increasing in the world from the past five years due to cancer. There are different types of cancers like skin, lung, breast, rectum, stomach, prostate, liver, cervix, oesophagus etc. The causes of these cancers may be both internal (genetic, mutations, poor immune conditions, hormonal problems) and external or environmental factors (food habits, industrialization, over growth of population etc.). To cure these types of cancers herbal remedies are more useful than synthetic treatment. Herbal treatment is the best replacement for treating /avoiding various physical side effects caused by the chemotherapy and radiation therapy. This treatment option can effectively avoid the damaging of normal, healthy cells near cancer cells. The present article discusses various natural herbs useful for the treatment of cancer. Various effective natural treatments for curing cancer were also described....
One of the species that emerged from the inventory of Gentiana family is Gentiana olivieri Griseb. Since this species have a particular occurrence in the nature and it’s still subjected to the ignorance and needs special treatment for the defined activity and the mode of action of drug. The plant is found in temperate region of Gulf countries and some temperate region of China. The objective of this paper was to establish chemical profile of Gentiana olivieri Griseb. using preliminary chemical tests and TLC studies. Identification of primary and secondary constituents has become the utmost important tool for the presence of active moiety. The phytochemical screening of petroleum ether, chloroform, acetone, ethanol, methanol and water extracts of Gentiana olivieri Aerial parts was done by chemical tests and TLC studies. Petroleum ether and chloroform extract showed the presence of fatty acids and alkaloids, acetone, methanol and ethanol extracts showed the presence of flavonoids and other phenolic compounds. While ethanol extract showed the presence of triterpenoids and some flavonoids. Ethyl acetate fraction was also prepared separately that showed the presence of biflavones. TLC profiling of above mentioned extracts showed the presence of at least 40 compounds that may be available belonging to different categories, which may be used to exploit the potential of this rare plant....
Number of plant species, crude extracts and phytoconstituents were proven for antimicrobial effects and can be used as a natural antiseptic to kill or inhibit the growth of microorganisms when applied to living tissue or skin and reduces the possibilities of infection, sepsis or putrefaction. The objective of the study was to formulate and evaluate the antimicrobial herbal ointment from the herbal crude extracts. The ethanolic extracts of the C. longa, R. cordifolia and aqueous extract of G. glabra plants were taken in different ratios by factorial designing approach and the antimicrobial tests of the extract combinations were performed. The most effective extract combination was determined by comparing the results of the zone of inhibition obtained from different extract ratios on Bacillus subtillus, Escherichia coli, Pseudomonas aeruginosa and Staphylococcous aureus species. The herbal ointment was prepared by incorporation of selected effective extract ratio into the selected ointment base using hot melting method. Prepared herbal ointment was evaluated for various semisolid dosage form parameters, stability study and antimicrobial effect. Herbal ointment was prepared using alcoholic extracts of C. longa, R. cordifolia and aqueous extract of G. glabra with antimicrobial potential....
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